EMBAR

Author:
Preeti Rawat, Sunil Kumar, Dr. Jitendra Kumar Malik
Preeti Rawat

Published Date: 19-Feb, 2023

Keywords: Herbal remedy, Anti-inflammatory, Boswellia serrata,Serratol, Thujene

Abstract:
Incense made from Boswellia resin has been used for centuries, along with the plant's essential oil, in alternative medical practises. Boswellia serrata, also known as Salai or Salai guggul, is a huge tree that spreads out over a wide area. It is native to the arid highlands of India, Northern Africa, and the Middle East. The incision in the tree trunk is tapped for oleo gum-resin, which is then kept in a bamboo basket to remove the oil content and harden. After extraction, gum-resin is sorted and categorised by taste, colour, form, and size. Boswellia serrata is mostly sourced from the Indian states of Andhra Pradesh, Gujarat, Madhya Pradesh, Jharkhand, and Chhattisgarh. It goes by a variety of names depending on where you are in the world. Thirty to sixty percent of oleo gum-resins are resin, five to ten percent are essential oils that are soluble in organic solvents, and the balance is polysaccharides. Boswellia serrata gum-resin extracts have a long history of usage in traditional medicine for the treatment of chronic inflammatory illnesses. The resinous portion of Boswellia serrata contains a wide variety of anti-inflammatory compounds. These compounds include monoterpenes, diterpenes, triterpenes, tetracyclic triterpenic acids, and four primary pentacyclic triterpenic acids. These primary acids are -boswellic acid, acetyl—boswellic acid, 11-keto—boswellic acid, and acety Inflammation is caused by an enzyme known as 5-lipoxygenase, and acetyl-11-keto-boswellic acid is the most efficient inhibitor of this enzyme.

References:

Alam A. Herbs that heal spices: The hoard of natural remedies. Ann Phytomed. 2019;8(2):7-18.

Zabihi O, Ahmadi M, Nikafshar S, Preyeswary KC, Naebe M. A technical review on epoxy-clay nanocomposites: Structure, properties, and their applications in fiber reinforced composites. Composites part b: engineering. 2018 Feb 15;135:1-24.

Yadav VK, Choudhary N, Heena Khan S, Khayal A, Ravi RK, Kumar P, Modi S, Gnanamoorthy G. Incense and incense sticks: types, components, origin and their religious beliefs and importance among different religions. J. Bio Innov. 2020;9:1420-39.

Balick M. Rodale's 21st-century Herbal: A Practical Guide for Healthy Living Using Nature's Most Powerful Plants. Rodale Books; 2014 Apr 29.

Johnson D. God is watching you: How the fear of God makes us human. Oxford University Press, USA; 2016.

Kumar SS, Bhosle D, Janghel A, Deo S, Raut P, Verma C, Agrawal M, Amit N, Sharma M, Giri T, Tripathi DK. Indian medicinal plants used for treatment of rheumatoid arthritis. Research Journal of Pharmacy and Technology. 2015;8(5):597-610.

Van Wyk BE. A family-level floristic inventory and analysis of medicinal plants used in Traditional African Medicine. Journal of ethnopharmacology. 2020 Mar 1;249:112351.

Spengler III RN. Fruit from the sands: the Silk Road origins of the foods we eat. Univ of California Press; 2019 Jul 23.

Siddiqui MZ. Boswellia serrata, a potential antiinflammatory agent: an overview. Indian journal of pharmaceutical sciences. 2011 May;73(3):255.

Warrier K, Muthupandiyan S. Boswellia serrata Roxb. Ex Coleb.: A Threatened Tree. International Journal of Plant & Soil Science. 2022 Dec 29;34(24):527-34.

Srivastava AK, Gupta D, Tiwari C, Kumar S, Rajput BS. Buchananialanzanspreng.(chironji) a potential wild fruit tree of peninsula India: A review. Journal of Progressive Agriculture. 2021;12(1):1-8.

Alamgir AN, Alamgir AN. Secondary metabolites: Secondary metabolic products consisting of C and H; C, H, and O; N, S, and P elements; and O/N heterocycles. Therapeutic Use of Medicinal Plants and their Extracts: Volume 2: Phytochemistry and Bioactive Compounds. 2018:165-309.

Batiha GE, Wasef L, Teibo JO, Shaheen HM, Zakariya AM, Akinfe OA, Teibo TK, Al-Kuraishy HM, Al-Garbee AI, Alexiou A, Papadakis M. Commiphora myrrh: a phytochemical and pharmacological update. Naunyn-Schmiedeberg's Archives of Pharmacology. 2022 Nov 18:1-6.

Mishra SU, Bishnoi RS, Maurya RA, Jain DE. Boswellia Serrata ROXB.?a Bioactive Herb with Various Pharmacological Activities. Asian J. Pharm. Clin. Res. 2020 Nov 7;13(11):33-9.

Shah S. Ayurveda: The conventional Indian medicine system and its global practice. Himalayan Journal of Health Sciences. 2019 Jan 26:13-33.

Sara BB, Sailaja AK. A review on polyherbal formulations used in the treatment of autoimmune disease like rheumatoid arthritis. Res. Rev. 2019;8:11-6.

Ayub MA, Hanif MA, Blanchfield J, Zubair M, Abid MA, Saleh MT. Chemical composition and antimicrobial activity of Boswellia serrata oleo-gum-resin essential oil extracted by superheated steam. Natural Product Research. 2022 Feb 17:1-6.

Suchita W, Raman DM, Kaur CD. A Review on phytochemistry and pharmacological activities of Boswellia serrata: A natural remedy. Int. J. Pharmacogn. 2021;8:454-61.

Roy A, Menon T. Evaluation of bioactive compounds from Boswellia serrata against SARS-CoV-2. Vegetos. 2022 Jun;35(2):404-14.

Gomaa AA, Mohamed HS, Abd-Ellatief RB, Gomaa MA. Boswellic acids/Boswellia serrata extract as a potential COVID-19 therapeutic agent in the elderly. Inflammopharmacology. 2021 Aug;29:1033-48.

Yu G, Xiang W, Zhang T, Zeng L, Yang K, Li J. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. BMC complementary medicine and therapies. 2020 Dec;20(1):1-6.

Alluri VK, Dodda S, Kilari EK, Golakoti T, Sengupta K. Toxicological assessment of a standardized Boswellia serrata gum resin extract. International Journal of Toxicology. 2019 Sep;38(5):423-35.

Bertocchi M, Isani G, Medici F, Andreani G, TubonUsca I, Roncada P, Forni M, Bernardini C. Anti-inflammatory activity of Boswellia serrata extracts: an in vitro study on porcine aortic endothelial cells. Oxidative medicine and cellular longevity. 2018 Jun 25;2018.

Beghelli D, Isani G, Roncada P, Andreani G, Bistoni O, Bertocchi M, Lupidi G, Alunno A. Antioxidant and ex-vivo immune system regulatory properties of Boswellia serrata extracts. Oxidative medicine and cellular longevity. 2017 Jan 1;2017.

Somasundaram SG, Oommen B. Antioxidant flavonoids for arthritis treatment: Human and animal models. Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases: Bioactive Food in Chronic Disease States. 2012 Oct 22:1.

Karl B, Alkhatib Y, Beekmann U, Bellmann T, Blume G, Steiniger F, Thamm J, Werz O, Kralisch D, Fischer D. Development and characterization of bacterial nanocellulose loaded with Boswellia serrata extract containing nanoemulsions as natural dressing for skin diseases. International Journal of Pharmaceutics. 2020 Sep 25;587:119635.

Kumar DS. Herbal bioactives and food fortification: extraction and formulation. CRC Press; 2015 Sep 25.